RESEARCH
ACHIEVEMENT

研究業績

当教室から公表された論文 等の著作物を年度別にご紹介いたします。

2018年度

*Yaguchi H, Yabe I, Takahashi H, Watanabe M, Nomura T, Kano T, Watanabe M, Hatakeyama S. J Neurol. 2018 Apr;265(4):962-965. doi: 10.1007/s00415-018-8785-z.

 

*Yabe I, Yaguchi H, Kato Y, Miki Y, Takahashi H, Tanikawa S, Shirai S, Takahashi I, Kimura M, Hama Y, Matsushima M, Fujioka S, Kano T, Watanabe M, Nakagawa S, Kunieda Y, Ikeda Y, Hasegawa M, Nishihara H, Ohtsuka T, Tanaka S, Tsuboi Y, Hatakeyama S, Wakabayashi K, Sasaki H.: Mutations in bassoon in individuals with familial and sporadic progressive supranuclear palsy-like syndrome. Sci Rep, 2018 Jan 16;8(1):819. doi: 10.1038/s41598-018-19198-0.

2017年度

Usuki F, Fujimura M, Yamashita A: Endoplasmic reticulum stress preconditioning modifies intracellular mercury content by upregulating membrane transporters, Sci Rep, 7(12390), 2017.

 

Uneda K, Wakui H, Maeda A, Azushima K, Kobayashi R, Haku S, Ohki K, Haruhara K, Kinguchi S, Matsuda M, Ohsawa M, Minegishi S, Ishigami T, Toya Y, Atobe Y, Yamashita A, Umemura S, Tamura K: Angiotensin II Type 1 Receptor-Associated Protein Regulates Kidney Aging and Lifespan Independent of Angiotensin, J Am Heart Assoc ,6(8): e006120, 2017.

 

Kobayashi R, Wakui H, Azushima K, Uneda K, Haku S, Ohki K, Haruhara K, Kinguchi S, Matsuda M, Ohsawa M, Toya Y, Nishiyama A, Yamashita A, Tanabe K, Maeshima Y, Umemura S, Tamura K: An angiotensin II type 1 receptor binding molecule has a critical role in hypertension in a chronic kidney disease model, Kidney Int, 91(5): 1115-1125, 2017.

 

Ohki K, Wakui H, Azushima K, Uneda K, Haku S, Kobayashi R, Haruhara K, Kinguchi S, Matsuda M, Ohsawa M, Maeda A, Minegishi S, Ishigami T, Toya Y, Yamashita A, Umemura S, Tamura K: ATRAP Expression in Brown Adipose Tissue Does Not Influence the Development of Diet-Induced Metabolic Disorders in Mice, Int J Mol Sci, 18(3): E676, 2017.

 

Yamashita A, Takeuchi O: Translational regulation by 3’UTR binding proteins, BMB Rep, 50(4) : 194-200, 2017.

 

Azushima K, Ohki K, Wakui H, Uneda K, Haku S, Kobayashi R, Haruhara K, Kinguchi S, Matsuda M, Maeda A, Toya Y, Yamashita A, Umemura S, Tamura K: Adipocyte-Specific Enhancement of Angiotensin II Type 1 Receptor-Associated Protein Ameliorates Diet-Induced Visceral Obesity and Insulin Resistance, J Am Heart Assoc, 6(3): e004488, 2017.

 

Yaguchi H, Yabe I, Takahashi H, Watanabe M, Nomura T, Kano T, Matsumoto M, Nakayama KI, Watanabe M, Hatakeyama S: Sez6l2 regulates phosphorylation of ADD and neuritogenesis. Biochem Biophys Res Commun, 494(1-2): 234-241, 2017.

 

Furukawa K T, Yamashita K, Sakurai N, Ohno S: The Epithelial Circumferential Actin Belt Regulates YAP/TAZ through Nucleocytoplasmic Shuttling of Merlin. Cell Rep, 20(6): 1435-1447, 2017.

 

Kawamura M, Umehara D, Odahara Y, Miyake A, Ngo M H, Ohsato Y, Hisasue M, Nakaya MA, Watanabe S, Nishigaki K: AKT capture by feline leukemia virus. Arch Virol, 162(4): 1031-1036, 2017. 

 

Yazaki M, Ito Y, Yamada M, Goulas S, Teramoto S, Nakaya MA, Ohno S, Yamaguchi K: Oral Ingestion of Collagen Hydrolysate Leads to the Transportation of Highly Concentrated Gly-Pro-Hyp and Its Hydrolyzed Form of Pro-Hyp into the Bloodstream and Skin. J Agric Food Chem, 65(11): 2315-2322, 2017. 

 

Kobayashi R, Wakui H, Azushima K, Uneda K, Haku S, Ohki K, Haruhara K, Kinguchi S, Matsuda M, Ohsawa M, Toya Y, Nishiyama A, Yamashita A, Tanabe K, Maeshima Y, Umemura S, Tamura K: An angiotensin II type 1 receptor binding molecule has a critical role in hypertension in a chronic kidney disease model. Kidney Int, 91(5):1115-1125, 2017. 

2016年度

Mizushima W, Takahashi H, Watanabe M, Kinugawa S, Mats ushima S, Takada S, Yokota T, Furihata T, Matsumoto J, Tsuda M, Chiba I, Nagashima S, Yanagi S, Matsumoto M, Nakayama K, Tsutsui H, *Hatakeyama S: The novel heart-specific RING finger protein 207 is involved in energy metabolism in cardiomyocytes. J Mol Cell Cardiol, 100, 43-53, 査読有, 2016.

 

Anwar D., Takahashi H., Watanabe M., Suzuki M., Fukuda S., *Hatakeyama S.: p53 represses the transcription of snRNA genes by preventing the formation of little elongation complex. BBA Gene Regulatory Mechanisms, 1859, 975-982, 査読有, 2016.

 

Fujieda Y., Amengual O., Matsumoto M., Kuroki K., Takahashi H., Kono M., Kurita Y., Otomo K., Kato M., Oku K., Bohgaki T., Horita T., Yasuda S., Maenaka K., Hatakeyama S., Nakayama K.I. and *Atsumi T.: Ribophorin II is involved in the tissue factor expression mediated by phosphatidylserine-dependent antiprothrombin antibody on monocytes. Rheumatology, 55, 1117-1126, 査読有, 2016.

 

Suzuki M., Watanabe M., Nakamaru Y., Takagi D., Takahashi H., Fukuda S. and *Hatakeyama S.: TRIM39 negatively regulates the NFkB-mediated signaling pathway through stabilization of cactin. Cell Mol Life Sci, 73, 1085-1101, 査読有, 2016.

 

Hayashi M, Maehara K, Harada A, Semba Y, Kudo K, Takahashi H, Oki S, Meno C, Ichiyanagi K, Akashi K, *Ohkawa Y. Chd5 Regulates MuERV-L/MERVL Expression in Mouse Embryonic Stem Cells Via H3K27me3 Modification and Histone H3.1/H3.2. J Cell Biochem., 117(3), 780-792, 査読有, 2016.

2015年度

Masuda Y, Takahashi H, Sato S, Tomomori-Sato C, Saraf A, Washburn MP, Florens L, Conaway RC, Conaway JW, *Hatakeyama S. TRIM29 regulates the assembly of DNA repair proteins into damaged chromatin. Nat Commun, 6, 7299, 査読有, 2015.

 

Masuda, Y., Takahashi H, and *Hatakeyama, S.: TRIM29 regulates the p63-mediated pathway in cervical cancer cells. Biochim Biophy Acta-Mol Cell Res, 1853, 2296-2305, 査読有, 2015.

 

Watanabe M, Takahashi H, Saeki Y, Ozaki T, Itoh S, Suzuki M, Mizushima W, Tanaka K, *Hatakeyama S.: The E3 ubiquitin ligase TRIM23 regulates adipocyte differentiation via stabilization of the adipogenic activator PPARγ. Elife, 4, e05615, 査読有, 2015.

 

Tsukiyama T, Fukui A, Terai S, Fujioka Y, Shinada K, Takahashi H, Terry P. Yamaguchi, Ohba Y, and *Hatakeyama S.: Molecular role of RNF43 in canonical and noncanonical Wnt signaling. Mol Cell Biol, 35, 2007-2023, 査読有, 2015.

 

Takahashi H, Takigawa I, Watanabe M, Anwar D, Shibata M, Tomomori-Sato C, Sato S, Ranjan A, Seidel CW, Tsukiyama T, Mizushima W, Hayashi M, Ohkawa Y, Conaway JW, Conaway RC, *Hatakeyama S.: MED26 regulates the transcription of snRNA genes through the recruitment of little elongation complex. Nat Commun, 6, 5941, 査読有, 2015.

 

*Sato T, Takahashi H, Hatakeyama S, Iguchi A. and Ariga T.: The TRIM-FLMN protein TRIM45 directly interacts with RACK1 and negatively regulates PKC-mediated signaling pathway. Oncogene, 34, 1280-1291, 査読有, 2015.

2014年度

Yabe I, Tanino M, Yaguchi H, Takiyama A, Cai H, Kanno H, Takahashi I, Hayashi Y, Watanabe M, Takahashi H, Hatakeyama S, Tanaka S, *Sasaki H.: Pathology of frontotemporal dementia with limb girdle muscular dystrophy caused by a DNAJB6 mutation. Clin Neurol Neurosur, 127:10-12, 査読有, 2014.

 

Yaguchi H, Yabe I, Takahashi H, Okumura F, Takeuchi A, Horiuchi K, Kano T, Kanda A, Saito W, Matsumoto M, Nakayama KI, Hatakeyama S, *Sasaki H: Identification of anti-Sez6l2 antibody in a patient with cerebellar ataxia and retinopathy. J Neurol, 261(1):224-226, 査読有, 2014.

2012年度

Yasukawa T, Bhatt S, Takeuchi T, Kawauchi J, Takahashi H, Tsutsui A, Muraoka T, Inoue M, Tsuda M, Kitajima S, Conaway RC, Conaway JW, Trainor PA, *Aso T.: Transcriptional Elongation Factor Elongin A Regulates Retinoic Acid-Induced Gene Expression during Neuronal Differentiation of Embryonic Stem Cells. Cell Rep, 29;2(5):1129-1136, 査読有, 2012.

 

Yaguchi H, Okumura F, Takahashi H, Kano T, Kameda H, Uchigashima M, Tanaka S, Watanabe M, Sasaki H, *Hatakeyama S.: TRIM67 protein negatively regulates Ras activity through degradation of 80K-H and induces neuritogenesis. J Biol Chem, 287(15):12050-12059, 査読有, 2012.

2011年度

Takahashi H, Parmely TJ, Sato S, Tomomori-Sato C, Banks CA, Kong SE, Szutorisz H, Swanson SK, Martin-Brown S, Washburn MP, Florens L, Seidel CW, Lin C, Smith ER, Shilatifard A, Conaway RC, *Conaway JW.: Human Mediator Subunit MED26 Functions as a Docking Site for Transcription Elongation Factors. Cell, 146(1), 92-104, 査読有, 2011.

2010年度

20. Lin C, Smith ER, Takahashi H, Lai KC, Martin-Brown S, Florens L, Washburn MP, Conaway JW, Conaway RC, *Shilatifard A.: AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia. Mol Cell, 37(3), 429-437, 査読有, 2010.

2009年度

Takahashi H, Martin-Brown S, Washburn MP, Florens L, Conaway JW, *Conaway RC.: Proteomics reveals a physical and functional link between hepatocyte nuclear factor 4alpha and transcription factor IID. J Biol Chem, 284(47), 32405-32412, 査読有, 2009.

 

Aygün O, Xu X, Liu Y, Takahashi H, Kong SE, Conaway RC, Conaway JW, *Svejstrup JQ.: Direct inhibition of RNA polymerase II transcription by RECQL5. J Biol Chem, 284(35), 23197-23203, 査読有, 2009.

 

Matsumoto M, Oyamada K, Takahashi H, Sato T, Hatakeyama S and *Nakayama KI: Large-scale proteomic analysis of tyrosine phosphorylation induced by TCR or BCR activation reveals new signaling pathways. Proteomics, 9(13), 3549-3563, 査読有, 2009.

2008年度

Yao T, Song L, Jin J, Cai Y, Takahashi H, Swanson SK, Washburn MP, Florens L, Conaway RC, Cohen RE and *Conaway JW: Distinct Modes of Regulation of the Uch37 Deubiquitinating Enzyme in the Proteasome and in the Ino80 Chromatin-Remodeling Complex. Mol Cell, 31(6), 909-917, 査読有, 2008.

2006年度

Fujii Y, Yada M, Nishiyama M, Kamura T, Takahashi H, Tsunematsu R, Susaki E, Nakagawa T, Matsumoto A, *Nakayama KI.: Fbxw7 contributes to tumor suppression by targeting multiple proteins for ubiquitin-dependent degradation. Cancer Sci, 97 (8), 729–736, 査読有, 2006.

2005年度

Hara T, Kamura T, Kotoshiba S, Takahashi H, Fujiwara K, Onoyama I, Shirakawa M, Mizushima N, and *Nakayama KI.: Role of the UBL-UBA Protein KPC2 in Degradation of p27 at G1 Phase of the Cell Cycle. Mol Cell Biol, 25(21), 9292-9303, 査読有, 2005.

 

Takahashi H, Hatakeyama S, Saitoh H, *Nakayama KI.: Noncovalent SUMO-1 binding activity of thymine DNA glycosylase (TDG) is required for its SUMO-1 modification and colocalization with the promyelocytic leukemia protein. J Biol Chem, 280(7), 5611-5621, 査読有, 2005.

home > 研究業績

expand_less